1. Alias
Scopola seed, toothache seed, and wolfberry seed.
2. Plant morphology
Two year old herb, up to 1 meter tall, with sticky glandular hairs covering the entire plant. The roots are thick and fleshy, with a diameter of 2-3 centimeters. The stem of an annual plant is extremely short, with a lotus shaped leaf cluster at the base of the stem. The stem of a biennial plant elongates and branches, with alternate stems and leaves, no petioles, half stem at the base, ovate to oblong leaves measuring 4-10 cm in length and 2-6 cm in width, blunt or gradually pointed at the tip, and often with feather like shallow or deeply lobed edges. Flowers are solitary above the middle of the stem in the leaf axils, usually leaning towards one side, with no or only very short stems near the stem. The sepals are cylindrical, with 5 shallow lobes, and the flowers enlarge into a pot like shape after the flowers. The corolla is bell shaped, yellow with a purple purple purple color network, and has 5 stamens. They are inserted near the middle of the corolla tube, slightly extending outside the corolla. The ovary is 2-chambered, the stigma is head shaped, and has 2 shallow lobes. The capsule is hidden in the persistent calyx, oval in shape, and ruptures when mature. The seeds are small, nearly disc-shaped, and have many reticular pits.
3. Origin distribution
Born near villages, fields, roadsides, houses, and other places; There is cultivation. Distributed in Heilongjiang, Jilin, Liaoning, Inner Mongolia and other places.
4. Harvesting and processing
When the fruits are ripe in late summer and early autumn, cut off the aboveground parts or pull up the whole plant, dry it, seed it, wash it, remove impurities, and dry it.
5. Characteristics of medicinal herbs
The seeds are slightly kidney shaped or oval shaped, slightly flattened, with a diameter of about 1 millimeter, a brownish yellow or grayish yellow surface, and raised fine mesh patterns. The slightly pointed end has a dotted navel. The longitudinal section shows embryo curvature, 2 cotyledons, and obvious embryonic roots. Qi is absent, with a slightly pungent taste.
6. Sexual Taste Returning to the Classics
Warm in nature, bitter and pungent in taste. Guixin Meridian, Liver Meridian, and Stomach Meridian.
7. Effect and Function
Relieve spasms, relieve pain, calm the mind, and calm asthma. Belonging to the category of tranquilizers, it is a type of heart nourishing and calming medicine.
8. Clinical application
The dosage is 0.06-0.6 grams, taken orally and administered in pill powder, for the treatment of gastric spasms, pain, wheezing, cough, and madness. For external use, boil and wash with water, grind and apply, or burn and smoke.
9. Pharmacological research
It can cause temporary eye closure, lateral lying, and righting reflex messages, and has a synergistic effect with central inhibitory drugs. It can affect EEG and conditioned reflex, increase pain threshold, and have a certain intensity of analgesic effect. Interacting with neurotransmitters, it increases the release of acetylcholine and has an antagonistic effect on norepinephrine. It can relieve the inhibition of the vagus nerve on the heart, allowing the sympathetic nervous system to dominate, resulting in an increase in heart rate. The degree of acceleration varies depending on the strength of the vagus nerve's control over the heart. It has the effect of relieving vascular spasm, improving microcirculation, and increasing renal blood flow. Can excite the respiratory center. Accelerate breathing and counteract respiratory depression caused by hibernation drugs. Inhibits the secretion of respiratory glands and has the effect of relaxing bronchial smooth muscle. Affects body temperature and other effects during anesthesia. Scopolamine (its racemic form is atropine) and scopolamine are both anticholinergic drugs that can block M-cholinergic receptors, mainly manifested in inhibiting glandular secretion and spasmolysis, dilating pupils, relieving the inhibition of the vagus nerve on the heart, thereby accelerating heart rate. Atropine has a certain excitatory effect on the central nervous system, while scopolamine has a sedative effect. Scopolamine drugs can regulate microvascular diameter, reduce endothelial cell damage, improve blood rheology, and increase microvascular autonomic movement; Scopolamine drugs can alter the lipid state of biological membranes; Scopolamine has a certain analgesic effect and has a synergistic effect when used in combination with Duromeprazole. Adverse reactions: There have been multiple reports of accidental ingestion of Tianxianzi poisoning, with the main symptoms being dizziness, blurred vision, unstable standing, nausea and vomiting, manic talk, severe seizures, and coma.
10. Chemical composition
Containing 0.02% to 0.17% scopolamine and 0.01% to 0.08% scopolamine. It also contains Amanita, atropine, fatty oils, etc.
11. Usage taboos
It is highly toxic, please take it orally with caution and avoid excessive or continuous use. Pregnant women, patients with heart disease, tachycardia, and glaucoma are prohibited from taking it..
12. Compatibility prescription
① Treating dental caries: Tianxianzi burns smoke and uses a bamboo tube to touch her teeth, causing the smoke to stop the insect holes from appearing. (Guidelines for Diagnosis and Treatment)
② Drinking for a long time: Tianxianzi, Muxiang, Xunhuang, etc. At the end. Apply sheep fat onto green paper, sprinkle on top, and roll into a tube. Burn, smoke, and inhale. (Cui's usurpation of important positions)
③ Treating water diarrhea for a long time: Ten Qingzhou dried jujubes (removed from the core), filled with heavenly fairies: Zhading burned and preserved. Drink 3 grams of corn per serving. (Holy Blessing Formula)
④ Treatment for red and white dysentery, abdominal pain, and intestinal discomfort: 15g rhubarb and 30g Tianxianzi. Mash Luo into powder, take 3 grams each time, adjust the rice drink, before eating. (The Marvelous Accomplishment of the Pujifang)
⑤ For those who treat stone carbuncles as hard as stones and do not produce pus: vinegar and scopolamine powder. Apply it to the head. (From "Qian Jin Yao Fang")
⊙ The content of the article is for clinical reference only. Non TCM professionals are not allowed to test drugs.